So then first of all I am interested in the possibility of physical transformation.

First and foremost, histologists and the like, have established the rate of tissue turnover.
So working form that standpoint let us see:
Skin: full thickness turnover in 4 weeks
Muscle: full thickness in a maximum of 3 months.
Blood vessels: renewed in 2-3 months
Bones: full thickness in six months to an year

The other requirement is focus and a clear picture of where I want to be at the end of an year with this degree of clarity.

What do I need to establish? A clear picture of the final physical transformation (Check) I desire. Bring some changes in the picture so it is unique to you (eye color).

A clear idea, picture, practical aids and daily repetition of the changes desired in the:
Color and appearance of my skin
Tone, bulk, proportion and size of muscles
Blood and blood vessels: